The risk factors include:
- Smoking: is the single most important risk factor and increases risk by 9x
- Hypercholesterolaemia/hyperlipidaemia
- Hypertension: patients with PVD have higher mean pressure than controls (x3 increased risk)
- Diabetes Mellitus: significantly higher risk of PVD in this condition (x4 increased risk)
- Family history of cardiovascular disease
- Cardiac disease*
- Cerebrovascular disease*
* These conditions are also caused by atherosclerosis and hence their presence increases the likely hood of the patient having PVD